Aloin B, also known as isobarbaloin, is a diastereomer of aloin A (barbaloin) and an anthraquinone C-glycoside extracted from the latex of Aloe vera and related species. It features an aloe-emodin anthrone core glycosidically linked to a D-glucose unit at the C10 position with specific stereochemistry distinguishing it from Aloin A. This yellow crystalline compound functions primarily as a stimulant laxative by irritating the colonic mucosa and promoting peristalsis. Research indicates antimicrobial, antioxidant, and potential anti-inflammatory activities, though therapeutic use is restricted due to genotoxicity concerns and risk of electrolyte imbalance with chronic intake. It contributes to the bitter taste and yellow color of aloe exudates and is studied for possible anticancer mechanisms involving apoptosis induction in cell lines.