Asparagusic Acid

    1,2-Dithiolane-4-carboxylic acid

    C4H6O2S2

    Asparagusic acid, systematically named 1,2-dithiolane-4-carboxylic acid, is a sulfur-containing heterocyclic compound uniquely biosynthesized in asparagus (Asparagus officinalis). It features a five-membered 1,2-dithiolane ring fused with a carboxylic acid group at the 4-position. This molecule is responsible for the distinctive urinary odor observed after asparagus ingestion, arising from its metabolites such as methanethiol and dimethyl sulfide. In plants, it contributes to defense against herbivores and pathogens via its reactive disulfide moiety. The strained ring system enables nucleophilic ring-opening reactions. It occurs at low concentrations (typically 1-10 mg/kg fresh weight) in asparagus spears. Limited studies explore its antioxidant potential and metabolic pathways in humans, where it is rapidly absorbed and excreted. Physical characteristics include a melting point near 76°C and stability under physiological conditions.

    Chemical Properties

    Volatility

    Non-volatile

    Does not evaporate readily — minimal aroma contribution

    Chemical Behavior

    Aroma Pattern:Aroma profile varies with temperature

    No sensory data available for this chemical component.