Demethoxycurcumin is a natural polyphenolic curcuminoid found in turmeric (Curcuma longa) rhizomes alongside curcumin and bisdemethoxycurcumin. It exhibits antioxidant, anti-inflammatory, antimicrobial, and potential anticancer activities. Structurally distinct from curcumin by the absence of one methoxy group on an aromatic ring, it may display altered bioavailability and potency. Research explores its roles in mitigating oxidative stress, inflammation, diabetes, and neurodegenerative conditions. In food applications, it contributes to turmeric's yellow color and is investigated for stability under varying pH, light, and heat conditions.