Gamma-linolenic acid (GLA) is an omega-6 fatty acid found in various plant seed oils, such as evening primrose oil, borage oil, and black currant seed oil. It is a polyunsaturated fatty acid with three double bonds, the first of which is located at the sixth carbon from the methyl end of the fatty acid chain. GLA is known for its anti-inflammatory properties and is used in dietary supplements to support skin health, reduce inflammation, and manage conditions like eczema and rheumatoid arthritis. In the body, GLA is converted to dihomo-gamma-linolenic acid (DGLA), which can be further metabolized into anti-inflammatory eicosanoids. Its role in food and nutrition is significant due to its potential health benefits and its presence in certain oils used in cooking and supplements.