Indole-3-carbinol (I3C) is a naturally occurring compound found in cruciferous vegetables such as broccoli, Brussels sprouts, cabbage, and kale. It is a product of the breakdown of glucobrassicin, a glucosinolate compound, when these vegetables are chewed or otherwise processed. I3C is of significant interest due to its potential health benefits, including its role in cancer prevention. It is believed to exert its effects through modulation of estrogen metabolism and induction of detoxifying enzymes. I3C is slightly soluble in water, highly soluble in alcohol, and slightly soluble in fats, which influences its bioavailability and absorption in the human body. Its stability can be affected by pH and temperature, and it can convert to various other compounds, such as diindolylmethane (DIM), under acidic conditions.