Sesamin is a major lignan compound abundant in sesame seeds and sesame oil. It belongs to the furofuran class of lignans and exhibits antioxidant, anti-inflammatory, and lipid-lowering properties. Research indicates potential benefits in modulating cholesterol metabolism, protecting against oxidative stress, and exhibiting neuroprotective effects. As a phytoestrogen, it interacts with estrogen receptors at low affinity. It is commonly studied for its role in cardiovascular health and as a dietary supplement derived from Sesamum indicum.